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CAS No.112901-68-5 | Anifostine trihydrate

CAS No.112901-68-5 | Anifostine trihydrate

Name: Anifostine trihydrate CAS No.112901-68-5 MF:C5H17N2O4PS MW:232.23 Purity:97% Package: 10g,25g,50g,100g,250g Worldwide Delivery

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Biochemicals

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Product introduction

Introduction and application of CAS No. 112901-68-5 | Anifostine trihydrate

Synonyms:Anifostinetrihydrate;

Ethanethiol,2-[(3-aMinopropyl)aMino]-,1-(dihydrogenphosphate),hydrate(1:3);

Amifostinetrihydrate,>=98%;

Aminopropylamino)ethylsulfanylphosphonicacidtrihydrate;

S-2-(3-AMINOPROPYLAMINO)ETHYLO,O-DIHYDROGENPHOSPHOROTHIOATE;

WR2721;Amifostinetrihydrateormonohydrate

Specification:

ITEMS	SPECIFICATION
CAS	112901-68-5
MF	C5H17N2O4PS
MW	232.23
Acidity coefficient	pKa1 <2.0; pKa2 4.2; pKa3 9.0; pKa4 11.7(at 25℃)
Solubility	PBS（pH 7.2）：5 mg/mL
Form	Powder
Storage condition	2-8°C

Overview:

Amifostine is a broad-spectrum cell protective agent that was once used as a military anti-radiation agent and is now used as a protective agent for radiotherapy and chemotherapy. It is highly effective in reducing the side effects of anti-cancer drugs such as cyclophosphamide, chloramphenicol, doxorubicin and anti-HIV drugs such as 3-azido-3-deoxythymidine without affecting the efficacy of anti-cancer drugs or anti-HIV drugs. Efficacy. Amifostine products currently on the market include freeze-dried powder for injection produced by American Life Sciences Co., Ltd., with the trade name ETHYOL. The product is only available as a lyophilized powder for injection, but the amorphous form produced by low-pressure lyophilization is thermally unstable.

Biological activity:

Amifostine trihydrate was the first antiradiation drug approved to reduce the risk of kidney disease associated with cisplatin treatment.

use:

Can be used as an adjuvant therapeutic agent for tumor radiotherapy or cytotoxic chemotherapy

Package and transportation :

Package: 10g,25g,50g,100g,250g